JLB Early View - Jan. 2022

Cover Image Journal of Leukocyte Biology

Early View

Online Version of Record before inclusion in an issue

MEETING ARTICLES

CCAAT/enhancer binding protein (C/EBP) delta promotes the expression of PTX3 and macrophage phagocytosis during A. fumigatus infection
Lulu Liu, Jinjin Zhong, Bilin Chen, Weiping Wang, Haiyan Xi, Xin Su

Version of Record online:23 December 2021


Graphical Abstract

CEBPD can regulate PTX3 during A. fumiagatus infection.

Open Access

ARTICLES

The anti‐inflammatory peptide Catestatin blocks chemotaxis
Elke M. Muntjewerff, Kristel Parv, Sushil K. Mahata, N. Koen van Riessen, Mia Phillipson, Gustaf Christoffersson, Geert van den Bogaart

Version of Record online:22 December 2021


Graphical Abstract

Catestatin blocks monocyte and granulocyte migration toward inflammatory chemokines.

Open Access

ARTICLES

Bone marrow microenvironment drives AML cell OXPHOS addiction and AMPK inhibition to resist chemotherapy
Ruolan You, Diyu Hou, Bin Wang, Jingru Liu, Xiaoting Wang, Qirong Xiao, Zhipeng Pan, Dongliang Li, Xiaoming Feng, Lixia Kang, Ping Chen, Huifang Huang

Version of Record online:20 December 2021


Graphical Abstract

Stromal contact renders AML cells chemoresistance by promoting AML cells' OXPHOS activity and OXPHOS's mechanism of action involves AMPK-mTORC1 pathway.

ARTICLES

Differential expression of maturation and activation markers on NK cells in patients with active and latent tuberculosis
Nurhan Albayrak, Violette Dirix, Laetitia Aerts, Anne Van Praet, Audrey Godefroid, Nicolas Dauby, Patricia Windey, Inge Muylle, Françoise Mascart, Véronique Corbière

Version of Record online:10 December 2021


Graphical Abstract

Whereas the numbers of the main NK cells subsets are normal in M. tuberculosis-infected patients, detailed phenotypic characterization revealed several differences related to functional modifications.

HIGHLIGHTED ARTICLE

Specific innate immune cells uptake fetal antigen and display homeostatic phenotypes in the maternal circulation
Marcia Arenas-Hernandez, Roberto Romero, Meyer Gershater, Li Tao, Yi Xu, Valeria Garcia-Flores, Errile Pusod, Derek Miller, Jose Galaz, Kenichiro Motomura, George Schwenkel, Robert Para, Nardhy Gomez-Lopez

Version of Record online:10 December 2021


Graphical Abstract

Novel interactions demonstrated between specific maternal circulating innate immune cells and fetal antigens that may contribute to the systemic mechanisms of maternal-fetal crosstalk.

SOLICITED REVIEWS

Dickkopf proteins in pathological inflammatory diseases
Min Hee Park, Jae Hun Shin, Alfred L.M. Bothwell, Wook-Jin Chae

Version of Record online:10 December 2021


Graphical Abstract

Review on Dickkopf family proteins as immunomodulatory ligands in cancer and other inflammatory diseases.

Open Access

HIGHLIGHTED ARTICLE

Kindlin‐3 maintains marginal zone B cells but confines follicular B cell activation and differentiation
Andrea Härzschel, Lixia Li, Peter W. Krenn, Eva Szenes-Nagy, Geoffroy Andrieux, Elisabeth Bayer, Dietmar Pfeifer, Laura Polcik, Ursula Denk, Jan P. Höpner, Elif Karabatak, Danielle-Justine Danner, Simone Tangermann, Lukas Kenner, Hassan Jumaa, Richard Greil, Melanie Börries, Raphael Ruppert, Palash C. Maity, Tanja Nicole Hartmann

Version of Record online:10 December 2021


Graphical Abstract

Kindlin-3 is a control point of proliferation and differentiation of follicular B cells and required to maintain marginal zone B cells.