Review of the mechanisms involved in HIV-1 cell-to-cell transfer to myeloid cells.

Patients recovered from COVID-19 present loss of the ΔΨ_m in HPBMC, leading to mitochondrial dysfunction, which is associated with the onset and progression of several chronic diseases such as pulmonary fibrosis, Alzheimer's, Parkinson's, and multiple sclerosis. Therefore, determining the ΔΨ_m in patients recovered from SARS-CoV-2 could be an early sign of several diseases caused by post-COVID-19 sequelae.

Polarized SC-derived macrophages may with some restrictions serve as a model for M1 but not for M2 macrophages.

Engineered neutrophil progenitors protect against the invasive fungal pathogens, Candida and Aspergillus, in a neutropenic mouse model

Review on mechanisms for selective elimination of host cells harboring replication-competent HIV by a combination of latency reversal with inhibition of pro-survival anti-apoptotic molecules and autophagy.

Discussion of the 60-year history of development of granulocyte replacement therapies provides background for the report of Sykes et al in this issue of the Journal.

Engraftment of rhesus macaque hematopoietic tissues in immune-deficient mice yields a robust BLT/NeoThy-type primatized mouse model for studying non-human primate hematopoiesis and immune function in vivo.

K48 and K27 ubiquitination contribute to regulating immune function of bone marrow precursor cells by affecting cross-presentation and thereby might be therapeutic target

Tumor-intrinsic CD21 impairs the target cell recognition and the cytotoxicity of the CD19-CAR-T cells.

Data to support model that Gab2 promotes AML progression through the SHP2-Erk-CREB pathway.

In severe COVID-19 patients, VIP plasma levels correlated with decreased inflammatory markers and survival. In in vitro assays with monocytes and lung epithelial cells, VIP and PACAP were found to decrease SARS-CoV-2 RNA synthesis (monocytes) and viral replication (lung epithelial cells). Both neuropeptides also reduced inflammatory factors and cell death of infected cells.

Review of how flavonoids control microglial activation states through regulation of microRNAs and the implications in Alzheimer's disease appearance and progression.

Differential cytokine response in endotoxin induced M-MDSC-like cells and their associated regulators.

Review on the structures, physiological functions, inhibitors of LUBAC, and related diseases caused by LUBAC aberration, providing comprehensively insight into LUBAC research.

Erf transcriptional factor is a positive regulator of thymocyte maturation towards CD4 and CD8 commitment while negatively regulates γδ generation.

Our study provides evidence of alterations in lymphocyte counts, memory T cell subset frequencies and common γ-chain cytokines in convalescent COVID-19 individuals.

Analysis of infiltrating T cells from NK-AML (M4/M5) patients using single-cell sequencing reveals distinct clusters and clonal expansion of immune T cells.

TRPM8 in human monocytes promotes aspects of their differentiation to macrophages and acts at a critical early time point to limit inflammatory potential.