Discussion on the role of kindlin-3 in regulation of integrin function, B cell homing, cross-talk with the CXCR5:CXCL13 axis and B cell activation.

Kindlin-3 is a control point of proliferation and differentiation of follicular B cells and required to maintain marginal zone B cells.

Interference with lncRNA SNHG3 is involved in cerebral ischemia-reperfusion injury by inhibiting microglial activation and the secretion of pro-inflammatory factors (TNF-α and IL-6). LncRNA SNHG3 could bind and stabilize HDAC3 protein, and inhibit the ubiquitination of HDAC3.

Identification of MFN2 as a key regulator of leukocyte adhesion, integrin activation, actin polymerization, and maturation.

WASp activity regulates dendritic cell (DC) migration; DCs have a remarkable adaptation for migration under inflammatory conditions in vivo.

GATA2 deficiency leads to increased miR-181c, decreased MCL1, and enhanced cell death which may contribute to phenotypic features of cytopenia, immunodeficiency, and bone marrow failure.

MS4A tetraspan molecules are differentially expressed and regulated in myeloid cells under normal and pathological conditions.

Hemin-induced heme oxygenase (HO)-1 alleviates asthmatic airway inflammation by dendritic cells (DCs)-released extracellular vesicles (DCEVs).

Neutrophils from pediatric patients with diabetic ketoacidosis display a primed phenotype at baseline, but fail to prime further when stimulated with TNF-α.

Blood and pulmonary dendritic cells from sarcoidosis patients more potently induced a T cell response with Tbet expression and IFNγ production compared with monocytes.

Cardiopulmonary bypass does not immediately affect neutrophils functions.

Reviews several essential and recently discovered signaling pathways in B cell development; takes a look at diseases related to aberrant signals as well as newly developed strategies for treating these diseases.

Review on Dickkopf family proteins as immunomodulatory ligands in cancer and other inflammatory diseases.

Describes the functions of dendritic cell-derived extracellular vesicles in the context of antigen presentation, infection, cell death and immunotherapy.

Review of NK cell-based therapies for HIV infection