GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the synovium
Julio Cesar Fernández-Ruiz, Fátima de Lourdes Ochoa-González, Martín Zapata-Zúñiga, Eduardo Mondragon-Marín, Edgar E. Lara-Ramírez, Jose Luis Ruíz-Carrillo, Paola Amayrani DelaCruz-Flores, Esther Layseca-Espinosa, José Antonio Enciso-Moreno, Julio Enrique Castañeda-Delgado
Version of Record online: 27 September 2022
Graphical Abstract
: GPR15/GPR15L interaction promotes leukocyte chemotaxis to synovium in patients with RA, this interaction might be a therapeutic target.
ILC3‐like ILC2 subset increases in minimal persistent inflammation after acute type II inflammation of allergic rhinitis and inhibited by Biminkang: Plasticity of ILC2 in minimal persistent inflammation
Xiang-Jing Chen, Cheng Liu, Shan Zhang, Li-Feng Zhang, Wei Meng, Xin Zhang, Meng Sun, Yue Zhang, Ren-Zhong Wang, Cheng-Fang Yao
Version of Record online: 26 September 2022
Graphical Abstract
ILC3-like ILC characterized with IL-5+IL-17A+IL-23R+ was significantly increased of the airway in minimal persistent inflammation and it could be inhibited by the Chinese herbal medicine Biminkang.
Open Access
Shock and kill within the CNS: A promising HIV eradication approach?
Marieke M. Nühn, Stephanie B. H. Gumbs, Ninée V. E. J. Buchholtz, Lisanne M. Jannink, Lavina Gharu, Lot D. de Witte, Annemarie M. J. Wensing, Sharon R. Lewin, Monique Nijhuis, Jori Symons
Version of Record online: 23 September 2022
Graphical Abstract
Review on the obstacles and limitations of using the shock and kill strategy to eradicate the HIV CNS reservoir.
Galectin‐3 as a biomarker in breast neoplasms: Mechanisms and applications in patient care
Doudou Georges Massar Niang, Folly Mawulolo Gaba, Adame Diouf, Jacobus Hendricks, Rokhaya Ndiaye Diallo, Maguette Deme Sylla Niang, Babacar Mbengue, Alioune Dieye
Version of Record online: 20 September 2022
Graphical Abstract
Review of the mechanisms involved in galectin-3 breast neoplasms promotion through the tumor microenvironment.
Advanced age is associated with changes in alveolar macrophages and their responses to the stress of traumatic injury
Devin M. Boe, Holly J. Hulsebus, Kevin M. Najarro, Juliet E. Mullen, Hyunmin Kim, Aik Choon Tan, Rachel H. McMahan, Elizabeth J. Kovacs
Version of Record online: 19 September 2022
Graphical Abstract
Healthy aging alters alveolar macrophage phenotype and responses to acute physiologic distress involving age-associated dysregulation of glucocorticoid signaling.
IL‐1β/NF‐κB signaling inhibits IGF‐1 production via let‐7f‐5p in dendritic epidermal T cells
Yashu Li, Juan Wang, Yangping Wang, Weifeng He, Yixin Zhang, Yan Liu
Version of Record online: 19 September 2022
Graphical Abstract
Molecular mechanisms identified by which IL-1β/NF-κB down-regulates IGF-1 expression by let-7f-5p in dendritic epidermal T cells.
γδ T cells: The potential role in liver disease and implications for cancer immunotherapy
He Ren, WanJing Li, Xin Liu, Na Zhao
Version of Record online: 13 September 2022
Graphical Abstract: Review on the molecular mechanisms of γδ T cells in liver disease and its implications for clinical immunotherapy.
Role of macrophages in HIV pathogenesis and cure: NIH perspectives
Jeymohan Joseph, William Daley, Diane Lawrence, Eric Lorenzo, Peter Perrin, Vasudev R. Rao, Shang-Yi Tsai, Vasundhara Varthakavi
Version of Record online: 08 September 2022
Graphical Abstract
Overview of interests and activities of NIH institutes involved in supporting research on macrophages and HIV
The role of γδ T17 cells in cardiovascular disease
Shaoxue Ling, Zonghao You, Yang Li, Jian Zhang, Shuwu Zhao, Yongzhi He, Xi Chen
Version of Record online: 08 September 2022
Graphical Abstract
This review provides a more comprehensive understanding of the biology of γδ cells and their role in CVD.
Dectin‐1 signaling in neutrophils up‐regulates PD‐L1 and triggers ROS‐mediated suppression of CD4+ T cells
M. Elizabeth Deerhake, Emre D. Cardakli, Mari L. Shinohara
Version of Record online: 08 September 2022
Graphical Abstract
Mechanisms by which Dectin-1 signaling in neutrophils promotes a cellular phenotype with T cell-suppressive properties.
The prognostic value of a 4‐factor neoimmunologic score system in non‐small cell lung cancer
Fan Yang, Ziqing Zeng, Yuan Li, Dong Zhang, Feng Wei, Hua Zhao, Peng Zhang, Xiubao Ren
Version of Record online: 08 September 2022
Graphical Abstract
A neoimmunologic score system was constructed based on 4 variables including CD3+, CD8+, FoxP3+, and PD-1+ immune cell densities in non-small cell lung cancer.