Discussion on systemic maternal immune cells aiding in maternal-fetal tolerance during pregnancy.

Novel interactions demonstrated between specific maternal circulating innate immune cells and fetal antigens that may contribute to the systemic mechanisms of maternal-fetal crosstalk.

Blocking acetyl-CoA carboxylases 1 and 2-(ACC1/2) deprives of fatty acids, through a fatty acid oxidation pathway, in activated dendritic cells (DC), inducing a semi-mature DC phenotype with a maturation-resistant feature.

Taurine up-regulated gene 1 (TUG1) reduces endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells and ameliorates diabetic nephropathy by inhibiting transcription factor PU.1.

Axl mediates mesangial cell phagocytosis of apoptotic cells and promotes mesangial cell proliferation by activating NF-kB and mTORC1.

Resting human monocytes have intracellular storage pools of CCL5 that are associated with compartments containing Rab11A and CD63, enabling rapid release without the need for de novo protein synthesis.

Extracellular vesicles produced by a melanoma cell line, MV3, induce phenotypic and functional changes in human neutrophils.

Unconventional T cells and NK cells require IL-12, monocytes, conventional T cells, and a mature immune system to efficiently respond to Staphylococcal enterotoxins in vitro.

In palmitate-conditioned wild type and diabetic mice macrophages, FOXO3a acetylation inhibits PINK1 expression and mitophagy leading to enhanced mtROS, mtDNA release, and inflammasome activation.

TLR and cytokine stimulation increase macrophage resistance to lysosomal damage through multiple distinct signaling pathways.

Urokinase-type plasminogen activator receptor and the function of nuclear paraspeckle assembly transcript 1 _1 in regulating rheumatoid arthritis fibroblast-like synoviocytes.

Fecal eosinophil-derived neurotoxin (F-EDN) levels are correlated to degranulation of eosinophils in the colon of irritable bowel syndrome (IBS) patients.

Macrophage functional plasticity of six macrophage phenotypes correlates with unique distinctions in cell-surface marker expression, signal protein secretion, transcriptomics profiles, and metabolic processes.

Reviews the role of IL-6, when generated in an inflammatory context or as derived from dendritic cells (DCs), in modulating the biological function and activation status of DCs.

Reviews the interaction between invariant natural killer T cells (iNKTs) and B cells and their impact on the treatment of infections, autoimmune diseases, cancers, and other diseases.

Review on the scientific premise for incidence of vaccine-induced thrombotic thrombocytopenia as a result of inflammatory reactions mediated via IL-1β/NLRP3 inflammasome activation and consequent overproduction of NETs.