p-JNK inhibitor treatment effectively revived human γδT cells from the apoptosis induced by IL-12/18 and maintained their enhanced IFN-γ production and cytotoxicity against tumor cells.

Ginsenoside Rg1 exerted an alleviating effect on SI-AKI, likely resulting from the inhibition of ferroptosis in renal TECs through FSP1.

Advanced age leads to significant disruption in function of alveolar macrophages, which play a critical role in tissue homeostasis and anti-microbial defense.

Immune ecosystem of dengue infection analyzed to provide insights into the pathogenesis and treatment.

Increased levels of early differentiated CD28⁺ CD27⁺ T lymphocytes at admission for pneumonia in older people is a predictor of better survival and no hospital readmission.

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Since IL-17A was produced by invariant natural killer T cells and CD3⁺CD56⁺αGalcer-CD1d tetramer^- T cells promote PBC-related fibrosis, they could be potentially used as a novel target for immunotherapy in the patients with primary biliary cholangitis.

Review of the current models to understand dynamic actions of macrophages in various diseases and new strategies to characterize their molecular network using single-cell transcriptomics.

B cells secrete IgG antibodies through a pathways that promotes exposure to the enzyme Fut8 to promote N-glycan core fucosylation, yet limits exposure to ST6Gal1 to minimize alpha2,6 sialylation.

A mechanism of temporal control of PMN-MDSC in newborns identified that involves lactoferrin mediated positive and type I interferon mediated negative regulation.

By inducing Klf10 expression, Mycobacterium tuberculosis decreases INF-γ production and impairs an INF-γ-mediated autocrine loop that promotes macrophages macropinocytosis, thus favoring survival and infection.

Overview of current strategies to kill HIV-1-infected cells.

Use of reverse vaccinology techniques to target multiple commonly misfolded proteins in ALS, such as SOD-1 and TDP-43.

Added data on circulating IL-6 levels can predict COVID-19 severity and IL1RA efficiency.

Study of human Vα7.2+CD161hi T cell distribution in peripheral blood and different sites of gastrointestinal tract, its TCR characteristics and response to Helicobacter pylori infection

R4 RGS proteins exhibit profound impact on the trafficking of blood stem cells and represent promising drug targets for enhancing clinical stem cell transplantation.

Data to support: (i) c-Rel-dependent monocytes (rMos) are a new subset of myeloid suppressor cells with a unique set of markers; and (ii) the differentiation of rMos is specified by a lineage-specific transcriptional complex called c-Rel enhanceosome.

ScRNA-seq of rhesus monkey microglia reveals clusters of cells in activated states in the setting of SIV infection, which is primarily reversed by suppressing viremia with combination antiretroviral therapy.

Th1 cells' function is suppressed in LUSC. Through scRNA-seq, the decreased Th1 cells' function is associated with ER stress, which requires further study.

Inflammatory acidosis represents a polarized neutrophil-epithelial dependent response independent of myeloperoxidase and ion efflux.

A trajectory analysis of circulating ILCs and adaptive T cell lymphocytes subtypes in patients spanning a cascade of gastric lesions.

IgM+ and IgM- MBCs that co-express CD73 and CD80 can differentiate into plasmablasts and germinal center B cells after re-challenge with P. yoelii.

Hyperactive ERK signaling alters the DC translatome and TACE activity to amplify inflammatory responses to TLR4 stimuli, potentially contributing to inflammation in Langerhans Cell Histiocytosis in mice.